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A co-formulation of supramolecularly stabilized insulin and pramlintide enhances meal-time glucagon suppression in diabetic pigs

In diabetic patients, treatment with insulin and pramlintide (an amylin analogue) is more effective than treatment with insulin only. But because mixtures of insulin and pramlintide are unstable and have to be injected separately, amylin analogues are only used by 1.5% of diabetics needing rapid-act...

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Detalhes bibliográficos
Publicado no:Nat Biomed Eng
Main Authors: Maikawa, Caitlin L., Smith, Anton A. A., Zou, Lei, Roth, Gillie A., Gale, Emily C., Stapleton, Lyndsay M., Baker, Sam W., Mann, Joseph L., Yu, Anthony C., Correa, Santiago, Grosskopf, Abigail K., Liong, Celine S., Meis, Catherine M., Chan, Doreen, Troxell, Megan, Maahs, David M., Buckingham, Bruce A., Webber, Matthew J., Appel, Eric A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7274092/
https://ncbi.nlm.nih.gov/pubmed/32393892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41551-020-0555-4
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