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A co-formulation of supramolecularly stabilized insulin and pramlintide enhances meal-time glucagon suppression in diabetic pigs

In diabetic patients, treatment with insulin and pramlintide (an amylin analogue) is more effective than treatment with insulin only. But because mixtures of insulin and pramlintide are unstable and have to be injected separately, amylin analogues are only used by 1.5% of diabetics needing rapid-act...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Biomed Eng
Prif Awduron: Maikawa, Caitlin L., Smith, Anton A. A., Zou, Lei, Roth, Gillie A., Gale, Emily C., Stapleton, Lyndsay M., Baker, Sam W., Mann, Joseph L., Yu, Anthony C., Correa, Santiago, Grosskopf, Abigail K., Liong, Celine S., Meis, Catherine M., Chan, Doreen, Troxell, Megan, Maahs, David M., Buckingham, Bruce A., Webber, Matthew J., Appel, Eric A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7274092/
https://ncbi.nlm.nih.gov/pubmed/32393892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41551-020-0555-4
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