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Rats are protected from the stress of chronic pressure overload compared with mice

The goal of this investigation was to compare the effects of chronic (4 wk) transverse aortic constriction (TAC) in Sprague-Dawley rats and C57BL/6J mice. TAC, after 1 day, induced similar left ventricular (LV) pressure gradients in both rats (n = 7) and mice (n = 7) (113 ± 5.4 vs. 103 ± 11.5 mmHg),...

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Bibliografske podrobnosti
izdano v:Am J Physiol Regul Integr Comp Physiol
Main Authors: Nishimura, Koichi, Oydanich, Marko, Zhang, Jie, Babici, Denis, Fraidenraich, Diego, Vatner, Dorothy E., Vatner, Stephen F.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7272766/
https://ncbi.nlm.nih.gov/pubmed/32209023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00370.2019
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