Acid exposure disrupts mucus secretion and impairs mucociliary transport in neonatal piglet airways

Tenacious mucus produced by tracheal and bronchial submucosal glands is a defining feature of several airway diseases, including cystic fibrosis (CF). Airway acidification as a driving force of CF airway pathology has been controversial. Here we tested the hypothesis that transient airway acidificat...

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Veröffentlicht in:Am J Physiol Lung Cell Mol Physiol
Hauptverfasser: Liao, Yan Shin J., Kuan, Shin Ping, Guevara, Maria V., Collins, Emily N., Atanasova, Kalina R., Dadural, Joshua S., Vogt, Kevin, Schurmann, Veronica, Bravo, Laura, Eken, Eda, Sponchiado, Mariana, Reznikov, Leah R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2020
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7272746/
https://ncbi.nlm.nih.gov/pubmed/32160007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00025.2020
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