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Acid exposure disrupts mucus secretion and impairs mucociliary transport in neonatal piglet airways

Tenacious mucus produced by tracheal and bronchial submucosal glands is a defining feature of several airway diseases, including cystic fibrosis (CF). Airway acidification as a driving force of CF airway pathology has been controversial. Here we tested the hypothesis that transient airway acidificat...

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Podrobná bibliografie
Vydáno v:Am J Physiol Lung Cell Mol Physiol
Hlavní autoři: Liao, Yan Shin J., Kuan, Shin Ping, Guevara, Maria V., Collins, Emily N., Atanasova, Kalina R., Dadural, Joshua S., Vogt, Kevin, Schurmann, Veronica, Bravo, Laura, Eken, Eda, Sponchiado, Mariana, Reznikov, Leah R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7272746/
https://ncbi.nlm.nih.gov/pubmed/32160007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00025.2020
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