Lactational metformin exposure programs offspring white adipose tissue glucose homeostasis and resilience to metabolic stress in a sex-dependent manner

We previously demonstrated that exposing mouse dams to metformin during gestation results in increased beta-cell mass at birth and increased beta-cell insulin secretion in adult male offspring. Given these favorable changes after a gestational maternal metformin exposure, we wanted to understand the...

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Bibliographic Details
Published in:Am J Physiol Endocrinol Metab
Main Authors: Carlson, Zach, Hafner, Hannah, Mulcahy, Molly, Bullock, Kaylie, Zhu, Allen, Bridges, Dave, Bernal-Mizrachi, Ernesto, Gregg, Brigid
Format: Artigo
Language:Inglês
Published: American Physiological Society 2020
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7272730/
https://ncbi.nlm.nih.gov/pubmed/32154743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00473.2019
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