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Gene expression regulation by CDK12: a versatile kinase in cancer with functions beyond CTD phosphorylation
Cyclin-dependent kinases (CDKs) play critical roles in cell cycle progression and gene expression regulation. In human cancer, transcription-associated CDKs can activate oncogenic gene expression programs, whereas cell cycle-regulatory CDKs mainly induce uncontrolled proliferation. Cyclin-dependent...
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| Publicado no: | Exp Mol Med |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7272620/ https://ncbi.nlm.nih.gov/pubmed/32451425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-020-0442-9 |
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