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Hexokinase 2 is dispensable for photoreceptor development but is required for survival during aging and outer retinal stress

Photoreceptor death is the ultimate cause of vision loss in many retinal degenerative conditions. Identifying novel therapeutic avenues for prolonging photoreceptor health and function has the potential to improve vision and quality of life for patients suffering from degenerative retinal disorders....

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Vydáno v:Cell Death Dis
Hlavní autoři: Weh, Eric, Lutrzykowska, Zuzanna, Smith, Andrew, Hager, Heather, Pawar, Mercy, Wubben, Thomas J., Besirli, Cagri G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7272456/
https://ncbi.nlm.nih.gov/pubmed/32499533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2638-2
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