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Photoreceptor metabolic reprogramming provides survival advantage in acute stress while causing chronic degeneration

Photoreceptor death is the root cause of vision loss in many retinal disorders, and there is an unmet need for neuroprotective modalities to improve photoreceptor survival. The biosynthetic requirement of photoreceptors is among the highest in the body, and to meet this demand, photoreceptors mainta...

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Detalhes bibliográficos
Publicado no:Sci Rep
Principais autores: Wubben, Thomas J., Pawar, Mercy, Smith, Andrew, Toolan, Kevin, Hager, Heather, Besirli, Cagri G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5736549/
https://ncbi.nlm.nih.gov/pubmed/29259242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18098-z
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