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Neural tube development depends on notochord-derived sonic hedgehog released into the sclerotome
Sonic hedgehog (Shh), produced in the notochord and floor plate, is necessary for both neural and mesodermal development. To reach the myotome, Shh has to traverse the sclerotome and a reduction of sclerotomal Shh affects myotome differentiation. By investigating loss and gain of Shh function, and f...
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| Publié dans: | Development |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Company of Biologists Ltd
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7272346/ https://ncbi.nlm.nih.gov/pubmed/32345743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.183996 |
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