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Neural tube development depends on notochord-derived sonic hedgehog released into the sclerotome

Sonic hedgehog (Shh), produced in the notochord and floor plate, is necessary for both neural and mesodermal development. To reach the myotome, Shh has to traverse the sclerotome and a reduction of sclerotomal Shh affects myotome differentiation. By investigating loss and gain of Shh function, and f...

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Bibliografski detalji
Izdano u:Development
Glavni autori: Kahane, Nitza, Kalcheim, Chaya
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists Ltd 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7272346/
https://ncbi.nlm.nih.gov/pubmed/32345743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.183996
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