Temozolomide and oral etoposide in children with recurrent malignant brain tumors

Despite advances in the treatment of brain tumors, the prognosis of children with recurrent malignant brain tumors remains poor. Etoposide (VP-16), an inhibitor of nuclear enzyme deoxyribonucleic acid (DNA)-topoisomerase II, has shown activity in brain tumors. Its efficacy appears schedule dependent...

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Detalhes bibliográficos
Publicado no:Drugs Context
Main Authors: Ruggiero, Antonio, Ariano, Anna, Triarico, Silvia, Capozza, Michele Antonio, Romano, Alberto, Maurizi, Palma, Mastrangelo, Stefano, Attinà, Giorgio
Formato: Artigo
Idioma:Inglês
Publicado em: BioExcel Publishing Ltd 2020
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7271709/
https://ncbi.nlm.nih.gov/pubmed/32547627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7573/dic.2020-3-1
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