Temozolomide and oral etoposide in children with recurrent malignant brain tumors

Despite advances in the treatment of brain tumors, the prognosis of children with recurrent malignant brain tumors remains poor. Etoposide (VP-16), an inhibitor of nuclear enzyme deoxyribonucleic acid (DNA)-topoisomerase II, has shown activity in brain tumors. Its efficacy appears schedule dependent...

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Bibliografiske detaljer
Udgivet i:Drugs Context
Main Authors: Ruggiero, Antonio, Ariano, Anna, Triarico, Silvia, Capozza, Michele Antonio, Romano, Alberto, Maurizi, Palma, Mastrangelo, Stefano, Attinà, Giorgio
Format: Artigo
Sprog:Inglês
Udgivet: BioExcel Publishing Ltd 2020
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7271709/
https://ncbi.nlm.nih.gov/pubmed/32547627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7573/dic.2020-3-1
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