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Temozolomide and oral etoposide in children with recurrent malignant brain tumors

Despite advances in the treatment of brain tumors, the prognosis of children with recurrent malignant brain tumors remains poor. Etoposide (VP-16), an inhibitor of nuclear enzyme deoxyribonucleic acid (DNA)-topoisomerase II, has shown activity in brain tumors. Its efficacy appears schedule dependent...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Drugs Context
Hauptverfasser: Ruggiero, Antonio, Ariano, Anna, Triarico, Silvia, Capozza, Michele Antonio, Romano, Alberto, Maurizi, Palma, Mastrangelo, Stefano, Attinà, Giorgio
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioExcel Publishing Ltd 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7271709/
https://ncbi.nlm.nih.gov/pubmed/32547627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7573/dic.2020-3-1
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