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A mechanistic approach to prove the efficacy of combination therapy against New Delhi metallo-β-lactamases producing bacterial strain: a molecular and biochemical approach

BACKGROUND: NDM-1 is a novel broad-spectrum metallo-β-lactamase with the capability to grant resistance to almost all β-lactam antibiotics. Its widespread dissemination made treatment options a major challenge to combat, causing threat to public health worldwide. Due to antibiotic resistance problem...

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Veröffentlicht in:Eur J Med Res
Hauptverfasser: Maryam, Lubna, Ali, Abid, Khalid, Shamsi, Khan, Asad U.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7271545/
https://ncbi.nlm.nih.gov/pubmed/32493479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40001-020-00418-1
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