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The role of testosterone in chronic kidney disease and kidney function in men and women: a bi-directional Mendelian randomization study in the UK Biobank

BACKGROUND: Chronic kidney disease (CKD) has an apparent sex disparity, with a more rapid progress in men than in women. Whether the well-established sex-specific evolutionary biology trade-off between reproduction and longevity might inform CKD has not previously been considered. Relevant evidence...

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Detalhes bibliográficos
Publicado no:BMC Med
Main Authors: Zhao, Jie V., Schooling, C. Mary
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7271464/
https://ncbi.nlm.nih.gov/pubmed/32493397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-020-01594-x
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