HMCES safeguards replication from oxidative stress and ensures error‐free repair

Replication across oxidative DNA lesions can give rise to mutations that pose a threat to genome integrity. How such lesions, which escape base excision repair, get removed without error during replication remains unknown. Our PCNA‐based screen to uncover changes in replisome composition under diffe...

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Bibliographic Details
Published in:EMBO Rep
Main Authors: Srivastava, Mrinal, Su, Dan, Zhang, Huimin, Chen, Zhen, Tang, Mengfan, Nie, Litong, Chen, Junjie
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2020
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Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7271331/
https://ncbi.nlm.nih.gov/pubmed/32307824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201949123
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