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HMCES safeguards replication from oxidative stress and ensures error‐free repair

Replication across oxidative DNA lesions can give rise to mutations that pose a threat to genome integrity. How such lesions, which escape base excision repair, get removed without error during replication remains unknown. Our PCNA‐based screen to uncover changes in replisome composition under diffe...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Srivastava, Mrinal, Su, Dan, Zhang, Huimin, Chen, Zhen, Tang, Mengfan, Nie, Litong, Chen, Junjie
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7271331/
https://ncbi.nlm.nih.gov/pubmed/32307824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201949123
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