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N1-Benzofused Modification of Fluoroquinolones Reduces Activity Against Gram-Negative Bacteria
[Image: see text] The fluoroquinolone class of antibiotics has a well-established structure–activity relationship (SAR) and a long history in the clinic, but the effect of electron-rich benzofused substituents at the N1 position remains poorly explored. Because groups at this position are part of th...
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| Publicado no: | ACS Omega |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2020
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7271024/ https://ncbi.nlm.nih.gov/pubmed/32548371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b03910 |
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