The μ-opioid receptor nonsynonymous variant 118A>G is associated with prolonged abstinence from heroin without agonist treatment

AIM: This study assesses whether opioid-related gene variants contribute to reduced vulnerability to relapse to heroin in persons who are not treated with μ-opioid receptor agonist. METHODS: Genotypes of 71 SNPs, in nine genes, were analyzed for association with long-term abstinence in former heroin...

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Publicado en:Pharmacogenomics
Autores principales: Levran, Orna, Peles, Einat, Randesi, Matthew, da Rosa, Joel Correa, Adelson, Miriam, Kreek, Mary Jeanne
Formato: Artigo
Lenguaje:Inglês
Publicado: Future Medicine Ltd 2017
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7270956/
https://ncbi.nlm.nih.gov/pubmed/28976288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs-2017-0092
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