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Inhibiting ULK1 kinase decreases autophagy and cell viability in high-grade serous ovarian cancer spheroids

Metastasis in high-grade serous ovarian cancer (HGSOC) occurs through an unconventional route that involves exfoliation of cancer cells from primary tumors and peritoneal dissemination via multicellular clusters or spheroids. Previously, we demonstrated autophagy induction in HGSOC spheroids grown i...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Singha, Bipradeb, Laski, Jeremi, Ramos Valdés, Yudith, Liu, Elaine, DiMattia, Gabriel E, Shepherd, Trevor G
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269771/
https://ncbi.nlm.nih.gov/pubmed/32509386
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