Inhibiting ULK1 kinase decreases autophagy and cell viability in high-grade serous ovarian cancer spheroids

Metastasis in high-grade serous ovarian cancer (HGSOC) occurs through an unconventional route that involves exfoliation of cancer cells from primary tumors and peritoneal dissemination via multicellular clusters or spheroids. Previously, we demonstrated autophagy induction in HGSOC spheroids grown i...

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Vydáno v:Am J Cancer Res
Hlavní autoři: Singha, Bipradeb, Laski, Jeremi, Ramos Valdés, Yudith, Liu, Elaine, DiMattia, Gabriel E, Shepherd, Trevor G
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2020
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269771/
https://ncbi.nlm.nih.gov/pubmed/32509386
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