Chargement en cours...
Truncated mutants of beta-glucosidase 2 (GBA2) are localized in the mitochondrial matrix and cause mitochondrial fragmentation
The enzyme β-glucosidase 2 (GBA2) is clinically relevant because it is targeted by the drug miglustat (Zavesca(®)) and because it is involved in inherited diseases. Mutations in the GBA2 gene are associated with two neurological diseases on the ataxia-spasticity spectrum, hereditary spastic parapleg...
Enregistré dans:
| Publié dans: | PLoS One |
|---|---|
| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2020
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7269613/ https://ncbi.nlm.nih.gov/pubmed/32492073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0233856 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|