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The multifaceted role of ischemia/reperfusion in sickle cell anemia

Sickle cell anemia is a unique disease dominated by hemolytic anemia and vaso-occlusive events. The latter trigger a version of ischemia/reperfusion (I/R) pathobiology that is singular in its origin, cyclicity, complexity, instability, perpetuity, and breadth of clinical consequences. Specific clini...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Hebbel, Robert P., Belcher, John D., Vercellotti, Gregory M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269579/
https://ncbi.nlm.nih.gov/pubmed/32118586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI133639
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