Early and prominent alterations in hemodynamics, signaling, and gene expression following renal ischemia in sickle cell disease

Acute ischemic insults to the kidney are recognized complications of human sickle cell disease (SCD). The present study analyzed in a transgenic SCD murine model the early renal response to acute ischemia. Renal hemodynamics were profoundly impaired following ischemia in sickle mice compared with wi...

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Detalhes bibliográficos
Main Authors: Juncos, Julio P., Grande, Joseph P., Croatt, Anthony J., Hebbel, Robert P., Vercellotti, Gregory M., Katusic, Zvonimir S., Nath, Karl A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853318/
https://ncbi.nlm.nih.gov/pubmed/20107113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00631.2009
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