Transgenic Sickle Mice Are Markedly Sensitive to Renal Ischemia-Reperfusion Injury

Ischemic injury is invoked as a mechanism contributing to end-organ damage and other complications of sickle cell disease (SCD). However, the intrinsic sensitivity of tissues in SCD to ischemic insults has never been addressed. We examined the effect of renal ischemia in a transgenic mouse expressin...

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Autors principals: Nath, Karl A., Grande, Joseph P., Croatt, Anthony J., Frank, Elena, Caplice, Noel M., Hebbel, Robert P., Katusic, Zvonimir S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2005
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Original Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602372/
https://ncbi.nlm.nih.gov/pubmed/15793278
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