Efficacy of Bedaquiline, Alone or in Combination with Imipenem, against Mycobacterium abscessus in C3HeB/FeJ Mice

Mycobacterium abscessus lung infections remain difficult to treat. Recent studies have recognized the power of new combinations of antibiotics, such as bedaquiline and imipenem, although in vitro data have questioned this combination. We report that the efficacy of bedaquiline-imipenem combination t...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Le Moigne, Vincent, Raynaud, Clément, Moreau, Flavie, Dupont, Christian, Nigou, Jérôme, Neyrolles, Olivier, Kremer, Laurent, Herrmann, Jean-Louis
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2020
Soggetti:
Experimental Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269509/
https://ncbi.nlm.nih.gov/pubmed/32253217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00114-20
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