MK-571, a Cysteinyl Leukotriene Receptor 1 Antagonist, Inhibits Hepatitis C Virus Replication

The quinoline MK-571 is the most commonly used inhibitor of multidrug resistance protein-1 (MRP-1) but was originally developed as a cysteinyl leukotriene receptor 1 (CysLTR1) antagonist. While studying the modulatory effect of MRP-1 on anti-hepatitis C virus (HCV) direct-acting antiviral (DAA) effi...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Ruiz, Isaac, Nevers, Quentin, Hernández, Eva, Ahnou, Nazim, Brillet, Rozenn, Softic, Laurent, Donati, Flora, Berry, Francois, Hamadat, Sabah, Fourati, Slim, Pawlotsky, Jean-Michel, Ahmed-Belkacem, Abdelhakim
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269486/
https://ncbi.nlm.nih.gov/pubmed/32179525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02078-19
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