Interaction between galectin-3 and cystinosin uncovers a pathogenic role of inflammation in kidney involvement of cystinosis

Inflammation is involved in the pathogenesis of many disorders. However, the underlying mechanisms are often unknown. Here, we test whether cystinosin, the protein involved in cystinosis, is a critical regulator of galectin-3, a member of the β-galactosidase binding protein family, during inflammati...

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Gepubliceerd in:Kidney Int
Hoofdauteurs: Lobry, Tatiana, Miller, Roy, Nevo, Nathalie, Rocca, Celine J., Zhang, Jinzhong, Catz, Sergio D., Moore, Fiona, Thomas, Lucie, Pouly, Daniel, Bailleux, Anne, Guerrera, Ida Chiara, Gubler, Marie-Claire, Cheung, Wai W., Mak, Robert H., Montier, Tristan, Antignac, Corinne, Cherqui, Stephanie
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269416/
https://ncbi.nlm.nih.gov/pubmed/30928021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2019.01.029
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