Interaction between galectin-3 and cystinosin uncovers a pathogenic role of inflammation in kidney involvement of cystinosis

Inflammation is involved in the pathogenesis of many disorders. However, the underlying mechanisms are often unknown. Here, we test whether cystinosin, the protein involved in cystinosis, is a critical regulator of galectin-3, a member of the β-galactosidase binding protein family, during inflammati...

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Publicado en:Kidney Int
Main Authors: Lobry, Tatiana, Miller, Roy, Nevo, Nathalie, Rocca, Celine J., Zhang, Jinzhong, Catz, Sergio D., Moore, Fiona, Thomas, Lucie, Pouly, Daniel, Bailleux, Anne, Guerrera, Ida Chiara, Gubler, Marie-Claire, Cheung, Wai W., Mak, Robert H., Montier, Tristan, Antignac, Corinne, Cherqui, Stephanie
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269416/
https://ncbi.nlm.nih.gov/pubmed/30928021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2019.01.029
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