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Interactions between soluble species of β-amyloid and α-synuclein promote oligomerization while inhibiting fibrillization

Aggregations of β-amyloid (Aβ) and α-synuclein (αS) into oligomeric and fibrillar assemblies are the pathological hallmarks of Alzheimer’s and Parkinson’s diseases, respectively. Although Aβ and αS affect different regions of the brain and are separated at the cellular level, there is evidence of th...

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Detalles Bibliográficos
Publicado en:Biochemistry
Main Authors: Candreva, Jason, Chau, Edward, Rice, Margaret E., Kim, Jin Ryoun
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269195/
https://ncbi.nlm.nih.gov/pubmed/31854188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00655
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