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Interactions between soluble species of β-amyloid and α-synuclein promote oligomerization while inhibiting fibrillization

Aggregations of β-amyloid (Aβ) and α-synuclein (αS) into oligomeric and fibrillar assemblies are the pathological hallmarks of Alzheimer’s and Parkinson’s diseases, respectively. Although Aβ and αS affect different regions of the brain and are separated at the cellular level, there is evidence of th...

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Bibliografiske detaljer
Udgivet i:Biochemistry
Main Authors: Candreva, Jason, Chau, Edward, Rice, Margaret E., Kim, Jin Ryoun
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269195/
https://ncbi.nlm.nih.gov/pubmed/31854188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00655
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