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Proteolytic and Nonproteolytic Activation Mechanisms Result in Conformationally and Functionally Different Forms of Coagulation Factor XIII A
Factor XIIIA (FXIIIA) is a transglutaminase that crosslinks intra- and extracellular protein substrates. FXIIIA is expressed as an inactive zymogen, and during blood coagulation, it is activated by removal of an activation peptide by the protease thrombin. No such proteolytic FXIIIA activation is kn...
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| Udgivet i: | FEBS J |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7269131/ https://ncbi.nlm.nih.gov/pubmed/31407850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.15040 |
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