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Turning the tide: targeting PfCRT to combat drug-resistant P. falciparum?

Resistance to the current first-line antimalarials threatens the control of malaria caused by the protozoan parasite Plasmodium falciparum and underscores the urgent need for new drugs with novel modes of action. Here, we present the argument that the parasite’s chloroquine resistance transporter (P...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Rev Microbiol
Prif Awduron: Small-Saunders, Jennifer L., Hagenah, Laura M., Fidock, David A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269106/
https://ncbi.nlm.nih.gov/pubmed/32300249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41579-020-0353-8
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