Pancreatic cancer-derived organoids – a disease modeling tool to predict drug response

BACKGROUND: Organotypic cultures derived from pancreatic ductal adenocarcinoma (PDAC) termed pancreatic ductal cancer organoids (PDOs) recapitulate the primary cancer and can be derived from primary or metastatic biopsies. Although isolation and culture of patient-derived pancreatic organoids were e...

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Publicat a:United European Gastroenterol J
Autors principals: Frappart, Pierre-Olivier, Walter, Karolin, Gout, Johann, Beutel, Alica K, Morawe, Mareen, Arnold, Frank, Breunig, Markus, Barth, Thomas FE, Marienfeld, Ralf, Schulte, Lucas, Ettrich, Thomas, Hackert, Thilo, Svinarenko, Michael, Rösler, Reinhild, Wiese, Sebastian, Wiese, Heike, Perkhofer, Lukas, Müller, Martin, Lechel, André, Sainz, Bruno, Hermann, Patrick C, Seufferlein, Thomas, Kleger, Alexander
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2020
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7268941/
https://ncbi.nlm.nih.gov/pubmed/32213029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2050640620905183
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