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Stem cell-derived organoids to model gastrointestinal facets of cystic fibrosis

Cystic fibrosis (CF) is one of the most frequently occurring inherited human diseases caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) which lead to ample defects in anion transport and epithelial fluid secretion. Existing models lack both access to early stages...

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Detalhes bibliográficos
Publicado no:United European Gastroenterol J
Main Authors: Hohwieler, Meike, Perkhofer, Lukas, Liebau, Stefan, Seufferlein, Thomas, Müller, Martin, Illing, Anett, Kleger, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548342/
https://ncbi.nlm.nih.gov/pubmed/28815024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2050640616670565
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