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Stem cell-derived organoids to model gastrointestinal facets of cystic fibrosis

Cystic fibrosis (CF) is one of the most frequently occurring inherited human diseases caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) which lead to ample defects in anion transport and epithelial fluid secretion. Existing models lack both access to early stages...

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Podrobná bibliografie
Vydáno v:United European Gastroenterol J
Hlavní autoři: Hohwieler, Meike, Perkhofer, Lukas, Liebau, Stefan, Seufferlein, Thomas, Müller, Martin, Illing, Anett, Kleger, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548342/
https://ncbi.nlm.nih.gov/pubmed/28815024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2050640616670565
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