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Stem cell-derived organoids to model gastrointestinal facets of cystic fibrosis

Cystic fibrosis (CF) is one of the most frequently occurring inherited human diseases caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) which lead to ample defects in anion transport and epithelial fluid secretion. Existing models lack both access to early stages...

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Bibliografiske detaljer
Udgivet i:United European Gastroenterol J
Main Authors: Hohwieler, Meike, Perkhofer, Lukas, Liebau, Stefan, Seufferlein, Thomas, Müller, Martin, Illing, Anett, Kleger, Alexander
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548342/
https://ncbi.nlm.nih.gov/pubmed/28815024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2050640616670565
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