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Stem cell-derived organoids to model gastrointestinal facets of cystic fibrosis

Cystic fibrosis (CF) is one of the most frequently occurring inherited human diseases caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) which lead to ample defects in anion transport and epithelial fluid secretion. Existing models lack both access to early stages...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:United European Gastroenterol J
Hauptverfasser: Hohwieler, Meike, Perkhofer, Lukas, Liebau, Stefan, Seufferlein, Thomas, Müller, Martin, Illing, Anett, Kleger, Alexander
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548342/
https://ncbi.nlm.nih.gov/pubmed/28815024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2050640616670565
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