Pancreatic Ductal Organoids React Kras Dependent to the Removal of Tumor Suppressive Roadblocks

Pancreatic ductal adenocarcinoma (PDAC) is still the Achilles heel in modern oncology, with an increasing incidence accompanied by a persisting high mortality. The developmental process of PDAC is thought to be stepwise via precursor lesions and sequential accumulation of mutations. Thereby, current...

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Veröffentlicht in:Stem Cells Int
Hauptverfasser: Perkhofer, Lukas, Engler, Melanie, Gout, Johann, Arnold, Frank, Morawe, Mareen, Breunig, Markus, Seufferlein, Thomas, Kleger, Alexander, Frappart, Pierre-Olivier
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2019
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545725/
https://ncbi.nlm.nih.gov/pubmed/31236113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/2079742
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