Pancreatic Ductal Organoids React Kras Dependent to the Removal of Tumor Suppressive Roadblocks

Pancreatic ductal adenocarcinoma (PDAC) is still the Achilles heel in modern oncology, with an increasing incidence accompanied by a persisting high mortality. The developmental process of PDAC is thought to be stepwise via precursor lesions and sequential accumulation of mutations. Thereby, current...

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Bibliographic Details
Published in:Stem Cells Int
Main Authors: Perkhofer, Lukas, Engler, Melanie, Gout, Johann, Arnold, Frank, Morawe, Mareen, Breunig, Markus, Seufferlein, Thomas, Kleger, Alexander, Frappart, Pierre-Olivier
Format: Artigo
Language:Inglês
Published: Hindawi 2019
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545725/
https://ncbi.nlm.nih.gov/pubmed/31236113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/2079742
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