Pancreatic Ductal Organoids React Kras Dependent to the Removal of Tumor Suppressive Roadblocks

Pancreatic ductal adenocarcinoma (PDAC) is still the Achilles heel in modern oncology, with an increasing incidence accompanied by a persisting high mortality. The developmental process of PDAC is thought to be stepwise via precursor lesions and sequential accumulation of mutations. Thereby, current...

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Detalhes bibliográficos
Publicado no:Stem Cells Int
Principais autores: Perkhofer, Lukas, Engler, Melanie, Gout, Johann, Arnold, Frank, Morawe, Mareen, Breunig, Markus, Seufferlein, Thomas, Kleger, Alexander, Frappart, Pierre-Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545725/
https://ncbi.nlm.nih.gov/pubmed/31236113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/2079742
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