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Pancreatic Ductal Organoids React Kras Dependent to the Removal of Tumor Suppressive Roadblocks

Pancreatic ductal adenocarcinoma (PDAC) is still the Achilles heel in modern oncology, with an increasing incidence accompanied by a persisting high mortality. The developmental process of PDAC is thought to be stepwise via precursor lesions and sequential accumulation of mutations. Thereby, current...

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Опубликовано в: :Stem Cells Int
Главные авторы: Perkhofer, Lukas, Engler, Melanie, Gout, Johann, Arnold, Frank, Morawe, Mareen, Breunig, Markus, Seufferlein, Thomas, Kleger, Alexander, Frappart, Pierre-Olivier
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545725/
https://ncbi.nlm.nih.gov/pubmed/31236113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/2079742
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