Pancreatic Ductal Organoids React Kras Dependent to the Removal of Tumor Suppressive Roadblocks

Pancreatic ductal adenocarcinoma (PDAC) is still the Achilles heel in modern oncology, with an increasing incidence accompanied by a persisting high mortality. The developmental process of PDAC is thought to be stepwise via precursor lesions and sequential accumulation of mutations. Thereby, current...

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Publicat a:Stem Cells Int
Autors principals: Perkhofer, Lukas, Engler, Melanie, Gout, Johann, Arnold, Frank, Morawe, Mareen, Breunig, Markus, Seufferlein, Thomas, Kleger, Alexander, Frappart, Pierre-Olivier
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545725/
https://ncbi.nlm.nih.gov/pubmed/31236113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/2079742
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