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Insulin-like growth factor receptor signaling in tumorigenesis and drug resistance: a challenge for cancer therapy
Insulin-like growth factors (IGFs) play important roles in mammalian growth, development, aging, and diseases. Aberrant IGFs signaling may lead to malignant transformation and tumor progression, thus providing the rationale for targeting IGF axis in cancer. However, clinical trials of the type I IGF...
Enregistré dans:
| Publié dans: | J Hematol Oncol |
|---|---|
| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7268628/ https://ncbi.nlm.nih.gov/pubmed/32493414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-020-00904-3 |
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