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Insulin-like growth factor receptor signaling in tumorigenesis and drug resistance: a challenge for cancer therapy

Insulin-like growth factors (IGFs) play important roles in mammalian growth, development, aging, and diseases. Aberrant IGFs signaling may lead to malignant transformation and tumor progression, thus providing the rationale for targeting IGF axis in cancer. However, clinical trials of the type I IGF...

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Dades bibliogràfiques
Publicat a:J Hematol Oncol
Autors principals: Hua, Hui, Kong, Qingbin, Yin, Jie, Zhang, Jin, Jiang, Yangfu
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7268628/
https://ncbi.nlm.nih.gov/pubmed/32493414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-020-00904-3
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