Genes Bound by ΔFosB in Different Conditions With Recurrent Seizures Regulate Similar Neuronal Functions

Seizure incidence is increased in Alzheimer’s disease (AD) patients and mouse models, and treatment with the antiseizure drug levetiracetam improves cognition. We reported that one mechanism by which seizures can exert persistent effects on cognition is through accumulation of ΔFosB, a transcription...

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Bibliographische Detailangaben
Veröffentlicht in:Front Neurosci
Hauptverfasser: Stephens, Gabriel S., Fu, Chia-Hsuan, St. Romain, Corey P., Zheng, Yi, Botterill, Justin J., Scharfman, Helen E., Liu, Yin, Chin, Jeannie
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7268090/
https://ncbi.nlm.nih.gov/pubmed/32536852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.00472
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