Genes Bound by ΔFosB in Different Conditions With Recurrent Seizures Regulate Similar Neuronal Functions

Seizure incidence is increased in Alzheimer’s disease (AD) patients and mouse models, and treatment with the antiseizure drug levetiracetam improves cognition. We reported that one mechanism by which seizures can exert persistent effects on cognition is through accumulation of ΔFosB, a transcription...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Stephens, Gabriel S., Fu, Chia-Hsuan, St. Romain, Corey P., Zheng, Yi, Botterill, Justin J., Scharfman, Helen E., Liu, Yin, Chin, Jeannie
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7268090/
https://ncbi.nlm.nih.gov/pubmed/32536852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.00472
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