White matter hyperintensities mediate gray matter volume and processing speed relationship in cognitively unimpaired participants

White matter hyperintensities (WMH) have been extensively associated with cognitive impairment and reductions in gray matter volume (GMv) independently. This study explored whether WMH lesion volume mediates the relationship between cerebral patterns of GMv and cognition in 521 (mean age 57.7 years)...

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Detalhes bibliográficos
Publicado no:Hum Brain Mapp
Main Authors: Brugulat‐Serrat, Anna, Salvadó, Gemma, Operto, Grégory, Cacciaglia, Raffaele, Sudre, Carole H., Grau‐Rivera, Oriol, Suárez‐Calvet, Marc, Falcon, Carles, Sánchez‐Benavides, Gonzalo, Gramunt, Nina, Minguillon, Carolina, Fauria, Karine, Barkhof, Frederik, Molinuevo, José L., Gispert, Juan D.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7267988/
https://ncbi.nlm.nih.gov/pubmed/31778002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hbm.24877
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