White matter hyperintensities mediate gray matter volume and processing speed relationship in cognitively unimpaired participants

White matter hyperintensities (WMH) have been extensively associated with cognitive impairment and reductions in gray matter volume (GMv) independently. This study explored whether WMH lesion volume mediates the relationship between cerebral patterns of GMv and cognition in 521 (mean age 57.7 years)...

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Vydáno v:Hum Brain Mapp
Hlavní autoři: Brugulat‐Serrat, Anna, Salvadó, Gemma, Operto, Grégory, Cacciaglia, Raffaele, Sudre, Carole H., Grau‐Rivera, Oriol, Suárez‐Calvet, Marc, Falcon, Carles, Sánchez‐Benavides, Gonzalo, Gramunt, Nina, Minguillon, Carolina, Fauria, Karine, Barkhof, Frederik, Molinuevo, José L., Gispert, Juan D.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Inc. 2019
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7267988/
https://ncbi.nlm.nih.gov/pubmed/31778002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hbm.24877
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