Baricitinib counteracts metaflammation, thus protecting against diet-induced metabolic abnormalities in mice

OBJECTIVE: Recent evidence suggests the substantial pathogenic role of the Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway in the development of low-grade chronic inflammatory response, known as “metaflammation,” which contributes to obesity and type 2 diabetes. In...

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Veröffentlicht in:Mol Metab
Hauptverfasser: Collotta, Debora, Hull, William, Mastrocola, Raffaella, Chiazza, Fausto, Cento, Alessia Sofia, Murphy, Catherine, Verta, Roberta, Alves, Gustavo Ferreira, Gaudioso, Giulia, Fava, Francesca, Yaqoob, Magdi, Aragno, Manuela, Tuohy, Kieran, Thiemermann, Christoph, Collino, Massimo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2020
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7267733/
https://ncbi.nlm.nih.gov/pubmed/32413585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2020.101009
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