Identification of AnnexinA1 as an Endogenous Regulator of RhoA, and Its Role in the Pathophysiology and Experimental Therapy of Type-2 Diabetes

Annexin A1 (ANXA1) is an endogenously produced anti-inflammatory protein, which plays an important role in the pathophysiology of diseases associated with chronic inflammation. We demonstrate that patients with type-2 diabetes have increased plasma levels of ANXA1 when compared to normoglycemic subj...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Purvis, Gareth S. D., Collino, Massimo, Loiola, Rodrigo A., Baragetti, Andrea, Chiazza, Fausto, Brovelli, Martina, Sheikh, Madeeha H., Collotta, Debora, Cento, Alessia, Mastrocola, Raffaella, Aragno, Manuela, Cutrin, Juan C., Reutelingsperger, Chris, Grigore, Liliana, Catapano, Alberico L., Yaqoob, Magdi M., Norata, Giuseppe Danilo, Solito, Egle, Thiemermann, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446914/
https://ncbi.nlm.nih.gov/pubmed/30972066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00571
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