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Reciprocal monoallelic expression of ASAR lncRNA genes controls replication timing of human chromosome 6

DNA replication occurs on mammalian chromosomes in a cell-type distinctive temporal order known as the replication timing program. We previously found that disruption of the noncanonical lncRNA genes ASAR6 and ASAR15 results in delayed replication timing and delayed mitotic chromosome condensation o...

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Vydáno v:RNA
Hlavní autoři: Heskett, Michael B., Smith, Leslie G., Spellman, Paul, Thayer, Mathew J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7266157/
https://ncbi.nlm.nih.gov/pubmed/32144193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.073114.119
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