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Delayed replication timing leads to delayed mitotic chromosome condensation and chromosomal instability of chromosome translocations

Chromosomal rearrangements are found in virtually all types of human cancers. We show that certain chromosome translocations display a delay in mitotic chromosome condensation that is associated with a delay in the mitosis-specific phosphorylation of histone H3. This delay in mitotic condensation is...

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Detalhes bibliográficos
Main Authors: Smith, Leslie, Plug, Annemieke, Thayer, Mathew
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC60865/
https://ncbi.nlm.nih.gov/pubmed/11698686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.241355098
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