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Delayed replication timing leads to delayed mitotic chromosome condensation and chromosomal instability of chromosome translocations
Chromosomal rearrangements are found in virtually all types of human cancers. We show that certain chromosome translocations display a delay in mitotic chromosome condensation that is associated with a delay in the mitosis-specific phosphorylation of histone H3. This delay in mitotic condensation is...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The National Academy of Sciences
2001
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC60865/ https://ncbi.nlm.nih.gov/pubmed/11698686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.241355098 |
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