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Molecular mechanism of BK channel activation by the smooth muscle relaxant NS11021

Large-conductance Ca(2+)-activated K(+) channels (BK channels) are activated by cytosolic calcium and depolarized membrane potential under physiological conditions. Thus, these channels control electrical excitability in neurons and smooth muscle by gating K(+) efflux and hyperpolarizing the membran...

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Detalles Bibliográficos
Publicado en:J Gen Physiol
Autores principales: Rockman, Michael E., Vouga, Alexandre G., Rothberg, Brad S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Rockefeller University Press 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7266150/
https://ncbi.nlm.nih.gov/pubmed/32221543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201912506
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